Johnston's Grocery Store, at 301 N. Picacho in Casa Grande, Arizona, is a historic building built around 1907.

It was listed on the National Register of Historic Places in 1985.

[1] It was deemed significant for its use of adobe, which was rarely used for commercial buildings at the time of its construction.

The building first served as a grocery store until 1932, first operated by Johnston and then by Wong Hong Chin.

[2] It was owned from 1920 to 1935 by George Washington Johnston.