Part of Asian Highway Route AH18, the highway stretches from its southern end at Jalan Wong Ah Fook and Jalan Tun Abdul Razak in the metropolitan area of Johor Bahru to the northern end at the underpass flyover with North–South Expressway Southern Route and Johor Bahru Eastern Dispersal Link Expressway around Pandan.

The highway became the backbone of the Johor Bahru road system linking Pandan to the city centre, and to the Johor–Singapore Causeway, before being surpassed by the Johor Bahru Eastern Dispersal Link Expressway in 2012.

Travellers coming from Jalan Masai Bahru would have to take the flyover which connects with Tebrau Highway, and travelling northbound without diverting into the road connecting carrefour would lead to vehicles turning off into Jalan Masai Lama.

Under the Ninth Malaysia Plan Project and Iskandar Regional Development Authority (IRDA), the main road between Ulu Tiram and Kota Tinggi was upgraded into dual-carriageway.

The upgrading works for the Sungai Tebrau bridge near Pandan began in 2013 and was expected to be completed on 2015.