It owes its current appearance to Sophie Amalie Moth who in the late 18th century altered it with the assistance of Caspar Frederik Harsdorff and Joseph Christian Lillie.

Jomfruens Egede traces its history back to 1346 when it was owned by Uffe Pedersen Neb, a loyal supporter of King Valdemar IV, and known as Egedegaard.

In 1931 the estate was bought by Count Adam Wilhelm Moltke who had inherited Bregentved from his father in 1818 and would later become the first Danish Prime Minister after the adoption of the Constitution of Denmark in 1849.

Moltke increased his holdings through several other acquisitions, acting as curator of Vallø and Vemmetofte and managing Knuthenborg for Count Frederik Marcus Knuth, the underage nephew of his wife.

When Christian Moltke inherited Lystrup and Jomfruens Egede from his father, he disrupted his diplomatic career which had brought him to both London and Vienna to concentrate on the management of his estates.