Manasse studied clarinet at the Juilliard School under David Weber.
[2] He has toured in Japan and southeast Asia with the New York Symphonic Ensemble and has played in Jerusalem, Tel Aviv and Osaka.
[2] He has been a guest soloist with the National Philharmonic, Symphony Nova Scotia, National Chamber Orchestra, New York Philharmonic, and the orchestras of Alabama, Annapolis, Bozeman, Dubuque, Evansville, Florida West Coast, Green Bay, Indianapolis, Jackson, Oakland East Bay, Pensacola, Princeton, and Richmond.
Manasse and his duo-partner, the pianist Jon Nakamatsu, are artistic directors of the Cape Cod Chamber Music Festival.
[3] He has been an associate professor of clarinet at the Eastman School of Music since 1995, a faculty member of Juilliard School in 2007, and a distinguished artist in residence at Lynn University's Conservatory of Music since 2008 in Boca Raton, Florida.