An officer of the Senior Foreign Service with the rank of Minister-Counselor, he served as the Coordinator of the Health Incident Response Task Force at the U.S. Department of State from November 2021 until his retirement.

After an assignment as a Congressional Fellow in the Policy Office of the Speaker of the United States House of Representatives, he was the Deputy Director of the U.S. State Department’s Office of Russian Affairs from 2000 until 2002, serving as Acting Director for several months in early 2002.

[1] After serving as the Director of the State Department's Office of South Central European Affairs, responsible for Albania, Bosnia and Herzegovina, Croatia, Kosovo, Montenegro, North Macedonia, and Serbia, Moore was the Ambassador and Head of the OSCE Mission to Bosnia and Herzegovina from 2014 to 2017.

In November 2021, Moore was named by Secretary of State Antony Blinken as Coordinator of the Health Incident Response Task Force[3] which coordinates "the Department and interagency’s response to anomalous health incidents for personnel and dependents".

In addition to English, Moore speaks Bosnian, Serbian, Croatian, and Lithuanian, and is conversant in Danish, German, and Russian.