[14] His work as a voice artist includes narrating an English language audiobook of the Quran in 2019.
[16][17] He is a Special Correspondent for The Jewish Chronicle newspaper,[18] covering investigations,[19] features[20] and major news stories.
[21] In 2020, Sacerdoti was part of a consortium of business and media figures[22][23] which acquired The Jewish Chronicle.
[24] It had announced its intention to seek a creditor's voluntary liquidation, with 54 journalists and support staff told they would be made redundant, an outcome which was avoided through the consortium's acquisition of the newspaper.
[37] As a journalist and a campaigner, Sacerdoti has made many high profile public statements about antisemitism and other racisms, as well as about the Holocaust.
[42][43][44] He argues that true anti-racism requires individuals to act fairly to protect each other, using the example of the Catholic priests and nuns who saved his father's life: "When faced with the question of what our duty is as citizens of the world, each of us can choose to make a difference, just as they did.
"[45] He is critical of the use of the acronyms BAME and BIPOC because they exclude Jewish, Gypsy, Roma and Travellers of Irish Heritage groups, and because they create "linguistic opacity.
[48] Sacerdoti also criticised children's author Roald Dahl's anti-Jewish racism, suggesting that his "antisemitic attitudes were, and probably remain, widespread among some parts of British society.