Gamboa started off as a stage actor, acting in plays produced by Philippine Educational Theater Association (PETA).
He did movies such as Enter the Ninja (1981), Bayaning 3rd World (1999) with Ricky Davao and Cris Villanueva, and Feng Shui (2004) starring Kris Aquino.
Gamboa's TV projects include Ful Haus (2007) with Vic Sotto and Pia Guanio, and Totoy Bato (2009) played by Robin Padilla.
He was included in the cast of Philippine TV series' Kahit Konting Pagtingin starring Angeline Quinto, Sam Milby and Paulo Avelino, premiered in ABS-CBN on January 28, 2013.
[3] In 2024, Gamboa was cast alongside Bini member Stacey Sevilleja in the music video of the song "Sining" (Art) by Dionela and Jay R.[4] He is one of the founders and the first artistic director of Barasoain Kalinangan Foundation, Inc. community theater in Malolos, Bulacan, of which he is a resident.