He won a bronze medal with the Buffaloes at the 2006 Mac's Midget Hockey Tournament, scoring two goals in the bronze-medal game against the Prince Albert Mintos.

[8] Eberle started his second major junior season by earning WHL Player of the Month honours for October 2007, totalling 16 goals and 26 points over 16 games for the Pats.

[22] He was named to Team WHL for the 2009 Subway Super Series (formerly known as the ADT Canada–Russia Challenge) and was selected as an alternate captain to Pats teammate Colten Teubert for Game 5.

[26] Eberle was selected as the winner of the Four Broncos Memorial Trophy as WHL Player of the Year, defeating Western Conference nominee Craig Cunningham of the Vancouver Giants.

[29] Soon after signing a contract with the Oilers, Eberle was assigned to their American Hockey League (AHL) affiliate, the Springfield Falcons, for the remainder of the 2008–09 season.

Several members within the Oilers organization were outspoken regarding the omission, including captain Shawn Horcoff and Head Coach Tom Renney, to which the League replied that Eberle would have been selected had he not been injured.

[57] He was also considered an early favourite for the Lady Byng Memorial Trophy as the league's most gentlemanly player as he recorded eight penalty minutes over 57 games.

[73] During the 2013 off-season, the Oilers hired Dallas Eakins as their 12th head coach in franchise history and Nugent-Hopkins suffered a shoulder injury after signing an extension to remain with the team.

[75] As Eberle struggled to produce throughout November, including experiencing an eight-game scoring drought, rumours began to spring about trade offers with the Philadelphia Flyers.

[78] After missing an early January game due to a knee injury, Eberle was reunited with Hall and Nugent-Hopkins while Yakupov joined David Perron.

[86] While the Oilers began their preseason play, Eakins added newly drafted Leon Draisaitl onto Eberle's line along with David Perron in an effort to boost their production.

[89] Under his new head coach, Eberle tallied his 250th career NHL point on January 20[90] and tied with Nugent-Hopkins and Hall for the team lead in scoring.

[99] During his absence, rookie Connor McDavid suffered a broken clavicle resulting in Draisaitl being called up to join Hall and Nugent-Hopkins on the Oilers' top line.

[106] The following week, the trio combined for 13 points in their 5–2 win over the Toronto Maple Leafs on February 11, 2016, as Eberle also recorded his first career NHL hat-trick.

[137] However, he continued to struggle to score and was called out by head coach Todd McLellan for his lack of production and his tentativeness to play in high-risk areas.

[141] Upon joining the Islanders, Eberle was expected to start the 2017–18 NHL season as the top-line right wing alongside John Tavares and Anders Lee.

Head coach Doug Weight was replaced with Barry Trotz and captain John Tavares left the team as an unrestricted free agent.

"[166] Eberle concluded the season scoring five goals through the final seven games[167] while the top line trio outscored opponents by a 6-2 margin in more than 122 minutes of 5-on-5 hockey.

[183] When the Islanders faced the Tampa Bay Lightning in the Eastern Conference Final, Eberle had accumulated three goals and eight assists for 11 points throughout the postseason.

[188] Eberle began the season on a goalless streak before scoring the first hat trick in franchise history on November 4, 2021, to lift the Kraken over the Buffalo Sabres.

[194] While Yanni Gourde and Riley Sheahan were in the NHL's COVID protocol, McCann joined Schwartz and Eberle as part of the Kraken's top six forward lines.

[219] On October 8, 2024, at the start of the 2024–25 season, Eberle was named the second captain in Kraken history, filling the vacancy left by Mark Giordano.

[229] Defeating Sweden 5–1 in the final, Eberle helped Canada to a record-tying fifth straight gold medal and was named by the coaching staff as one of the team's best three players.

He was selected as an alternate captain to Patrice Cormier along with fellow returnees Colten Teubert, Alex Pietrangelo and Stefan Della Rovere.

[243] Following his NHL rookie season, Eberle joined the Canadian men's team for the second consecutive year for the 2011 IIHF World Championship in Slovakia.

[244][245] In a game against the United States during the qualifying round, Eberle scored in a shootout, helping Canada to a 4–3 win, while also temporarily tying them for the lead in their pool.

[248] In 2012, The Sports Network named him the best Canadian World Junior player ever as he held the longest scoring streak in Team Canada history.

[249] At the 2015 World Championships, where Canada won the gold medal for the first time since 2007 with a perfect 10–0 record, Eberle finished second in scoring with 5 goals and 8 assists, one point behind tournament leader Jason Spezza.

[251][252] He attended high school at the Athol Murray College of Notre Dame in Wilcox, Saskatchewan, before moving to Calgary, Alberta, at age 15 with his parents and three siblings.

[256][257] In 2022, Eberle and his wife founded the Sticks and Strings Foundation, a charitable organization supporting youth literacy, childhood sports, music and nature.