She moved back to the European part of the Netherlands due to her election to the House of Representatives in 2021 as a member of the social liberal party Democrats 66 (D66).

[6] After completing her studies, Wuite worked for five years as a management consultant for the Gouda company KVA Groep, which mostly assists the public sector.

[1][2] She became director of the Sector Public Health, Social Development and Labor Affairs in 2008 and filled that position until she was appointed secretary-general of that ministry two years later.

[7] When the interim first Marlin-Romeo cabinet was formed in early 2018, Wuite became the Minister of Education, Culture, Youth and Sports on behalf of the United Democrats (UD).

[11] Wuite's term ended on 19 November 2019, and she subsequently became a strategic advisor at the Ministry of Education, Culture, Youth and Sports concerned with reconstruction projects in the aftermath of Hurricane Irma.

[13] Wuite was sworn in on 31 March as the body's first member of Sint Maarten descent and was her party's spokesperson for kingdom relations, art, culture, and media.

[16] Next to her career, Wuite served for about ten years (until 2016) on the board of the Caribbean chapter of the Prins Bernhard Cultuurfonds, a foundation providing funding for cultural activities.