Ferreyra was one of the most notable directors of the silent period of Argentine cinema, and later became an influence and also a participant of the Golden Age of Argentine cinema, famous for his melodramas with a strong tango content.
Ferreyra was born in Vicente López, Gran Buenos Aires.
His father was of White European descent, while his mother was Afro-Argentine, likely descended from slaves.
Ferreyra prevailes through the 1920s and 1930s as a distinguished filmmaker of the masses, but was displaced in the late 1930s and early 1940s by big budget cinema.
He directed over 40 films and wrote the scripts for the majority of them between 1915 and 1941, working with noted actors such as Libertad Lamarque and Mario Soffici on his screen debut, before moving on to directing.