[1] Arredondo made his MLB debut against the Chicago White Sox on May 14, 2008, at Angel Stadium in Anaheim, California.

Following a rough start to the 2009 season, Arredondo was optioned to the Angels' Triple-A affiliate, the Salt Lake Bees, on June 10.

"Arredondo chose not to, heading home to the Dominican instead", Orange County Register's Bill Plunkett reported.

His history of elbow injury and behavior issues, "seriously dented his standing with the Angels", wrote Plunkett, "and calls into question his future with the organization.

[6] He underwent Tommy John surgery (UCL reconstruction) in February and spent the summer of 2010 training at the Reds' facility in Goodyear, Arizona.

[7] Arredondo was with the Reds during spring training, but was placed on the 15-day DL to start the season so he could fully recover from his Tommy John surgery.

On July 29, in his first career major league at bat, Arredóndo, after pitching a perfect 13th against the Giants, singled to set up Édgar Rentería's game-ending hit.