Born in Lisbon and raised in the Bairro Alto neighbourhood,[3] Dominguez had an unassuming youth spell at his hometown club S.L.
[4] Following Luís Figo's departure to FC Barcelona, Sporting CP chose Dominguez as his replacement, and he went on to spend two solid seasons at the latter side, albeit with no silverware.
[6][7] Dominguez won the 1998–99 League Cup with Spurs as an unused substitute in the final,[8] but fell out of favour during the following season under George Graham, who demoted him to the reserves.
[13][14] After a brief spell in Qatar with Al Ahli SC,[15] Dominguez moved in 2005 to Brazil's CR Vasco da Gama.
[23] Dominguez later worked as assistant to his former Sporting teammate Ricardo Sá Pinto, at Gaziantep FK in Turkey and APOEL FC.
[24][25] After helping the latter to the Cypriot First Division title in 2023–24,[26] he was appointed their manager in August 2024,[27] being relieved of his duties two months later due to poor results.
[29] In his prime, he was noted for his pace, acceleration, agility, technique, flair and dribbling, and while at Benfica he often drew comparisons to Paulo Futre.