Although he was a lawyer by trade, his professional career was spent working promoting Latin American artists and their art for 50 years.

Gómez-Sicre was a critic, researcher and writer, publishing numerous reports and articles on Latin American artists.

Most importantly, Gómez-Sicre provided Latin American artists with an introduction to the audience in the United States and the world.

In 1944, he served as an advisor to Alfred H. Barr, Jr., of the Museum of Modern Art (MoMA) in New York City, putting together an exhibition of Cuban paintings that traveled across the United States for the next two years.

Gómez-Sicre served as editor for Boletin de Artes Visuales, an illustrated documentation of exhibitions throughout North America, which published from 1957-1973.