José Humberto Quintero Parra (September 22, 1902 – July 8, 1984) was the first Venezuelan Cardinal of the Roman Catholic Church.

He studied at the seminary in Mérida and the Pontifical Gregorian University in Rome (from where he obtained his doctorates in theology and canon law) before being ordained to the priesthood by Archbishop Filippo Cortesi on August 22, 1926.

Quintero then did pastoral work in Mérida until 1929, when he was named private secretary to the Archbishop of the same city, Acacio Chacón Guerra.

He received his episcopal consecration on the following December 6 from Adeodato Giovanni Piazza, OCD, with Archbishops Luigi Centoz and Giuseppe Misuraca serving as co-consecrators, in the chapel of the Collegio Pio Latinoamericano at Rome.

[1] During his tenure as Caracas' archbishop, he made an offer of mediation to Venezuela's guerrillas,[2] served as President of the Venezuelan Episcopal Conference, and enforced the "dignity and obligation of fatherhood".