For a time, he worked with an uncle who owned merchant ships in Montevideo which was occupied by the Brazilians, and then returned to Buenos Aires.

In January 1826 he enlisted in the fleet organized by Captain Guillermo Brown, and soon became an expert in river navigation on the Río de la Plata, Paraná and Uruguay.

He served in the small fleet of the besieged city, and for a time accompanied the privateer José Garibaldi on his excursion through the Paraná.

[3] Shortly before the Battle of Cepeda, in 1859 , he forced the passage of the Rosario batteries and stood in front of the city of Paraná.

The flagship was incorporated into the federal fleet; for several weeks, all of Buenos Aires believed that Captain Murature had also passed.

In January 1865 he commanded the Argentine squadron that gave support to the attack of the forces of Venancio Flores and his Brazilian allies on Paysandú; and intervened to try to prevent the murder of its defenders.

A Brazilian naval division that had joined his ship, the "National Guard" crossed the Paraguayan defense lines and their artillery, located in the ravines of the Paraná River.

He retired from the Argentine Navy after the end of the war, except for a sporadic service during the repression of the Entre Ríos leader Ricardo López Jordán.