José Maria dos Reis Pereira (17 September 1901 – 22 December 1969), better known by the pen name José Régio (Portuguese pronunciation: [ʒuˈzɛ ʁɛ.ʒju] zhoo-ZEH REH-zhyoo), was a Portuguese writer who spent most of his life in Portalegre (1929 to 1962).

In 1927 he founded the magazine Presença which would come to be a cornerstone of the Second Modernism [pt] movement in Portugal, of which he was the main spokesperson.

Aside from this magazine he also made contributions to newspapers such as the Diário de Notícias and the Comércio do Porto.

As a writer, José Régio was the author of novels, plays, poetry and essays.

His works are strongly focused on the theme of conflict between Man and God and between Individual and Society; in a critical analysis of solitude and human relations.