José Ramírez was born on January 21, 1990, in Yaguate, Dominican Republic to parents Silveria Mateo and Sito Ramirez.

[4] At the end of spring training the following year, the Yankees assigned Ramírez to the Trenton Thunder of the Class AA Eastern League.

[7] The Yankees promoted Ramírez to the major leagues on May 18 as the 26th man on their roster for a doubleheader, but he did not pitch and was optioned back to Scranton/Wilkes-Barre after the games.

[13] On December 4, 2015, the Mariners traded Ramírez to the Atlanta Braves for a player to be named later, who eventually became relief pitcher Ryne Harper.

[19] On September 14, 2016, Ramírez was ejected for the first time in his Major League career for throwing a pitch over the head of José Fernández.

[24] Ramírez did not play a game for the team due to the cancellation of the ALPB season because of the COVID-19 pandemic and became a free agent after the year.