Vidro is the first of three players, including Robinson Cancel (New York Mets) and Jonathan Sánchez (San Francisco Giants), from Sabana Grande to make it to the major leagues.

He also set career high numbers with 24 home runs and 97 RBI.

Vidro continued as the starting second baseman for the Expos in 2001 when he hit .319 with 15 home runs and 59 RBI.

Due to injuries to his right knee, ankle, and quadriceps muscle, Vidro played in only 87 games for the Washington Nationals in 2005, 8 of which were as a pinch hitter.

On December 14, 2006, the Nationals traded Vidro to the Seattle Mariners for outfielder Chris Snelling and pitcher Emiliano Fruto.