Spotted by a casting director, she asked her photographer uncle to take photos of her that she later slipped into an envelope with the message: "My name is Joséphine, I'm 8 years old, I want to be in the movies.

"[4][5] Two days later, the phone rang, the production company was worried because she had not specified her last name,[4] and she had been cast in the 2005 film Grey Souls, directed by Yves Angelo, which marked her acting debut.

[6] In 2014, she played the lead role of Charlie in the coming-of-age drama Breathe, directed by Mélanie Laurent, which was presented in the Critics' Week at the Cannes Film Festival.

[12] In 2023, she starred in the thriller Sur les chemins noirs [fr], directed by Denis Imbert; and portrayed Bernard Tapie's wife, Dominique Damianos, in the Netflix biographical miniseries Class Act.

Based on the true story of her younger sister, Bertille, who has a rare genetic disease that leads to autistic behavior,[14] it follows a family navigating the severe disability of the youngest daughter.