[1] He is currently a partner in the second largest multimedia group in his country, Grupo América, and has investments in several economic sectors, including energy, wine, and clothing.

Manzano is an experienced investor and frequently speaks around the world on issues such as investment, media, energy and distressed industries, according to the firm.

In 2024, he acquired lithium-rich acreage in northern Argentina and Brazil’s lithium valley, in order to mine for elements critical for the global clean energy transition.

In the power sector, Integra put together a large investment program of nearly $100 million dedicated to modernization and creation of an intelligent grid.

He acquired lithium-rich acreage in northern Argentina and Brazil’s lithium valley, investing in minerals expected to be important for the global transition to clean energy.

[16] Integra Capital also acquired Peruvian miner Volcan Cia Minera SAA from Glencore Plc, further increasing Manzano’s presence in the sector.

[1] Grupo Uno, in partnership with businessman Francisco de Narváez, acquired Buenos Aires TV channel América 2.

Manzano and Vila expanded Grupo Uno into Argentina’s second-largest media group, controlling key channels in the Cuyo region by the late 1990s.

[17][18][19] Today Grupo Uno consists of 40 media outlets throughout the country, including press, radio, television, and digital enterprises.

Among the major channels is América 2, located in Buenos Aires, whose operation license was renewed during President Néstor Kirchner's administration.

[25] With its extensive network of media services, the company reaches about 25 million people in Argentina and thus constitutes the second largest multimedia group in the country.

[29] The two men created Andes Energía, a Latin American energy group dedicated to the exploration, development and production of conventional and non-conventional oil and gas.

In July 2017, Andes Energía merged with Petrolera El Trebol (PETSA),[32] an Argentine subsidiary of Switzerland's Mercuria.

The merger created the new company Phoenix Global Resources and it has a strong presence in the country's most prolific conventional and non-conventional oil basins.

[37] Within the last few years, the business has been awarded exploitation contracts in southern Argentina, an area of great oil extraction potential.

[38] In 2013, Vila and Manzano bought 49.9% of the UTE (Transitory Union of Companies) led by El Trebol to exploit the Chañares Herrados and Puesto Pozo Cercado deposits in Tupungato (concessioned until 2017).

Pamar S.A. was recognized as the leader of the "Central West Gas Pipeline System",[42] the largest of its kind in Argentina, covering more than 500 kilometers.

[46] Manzano has expressed optimism about the country's economy under President Javier Milei, particularly the administration’s approach to inflation control and market liberalization.

[47] He said he believed the government’s policies were starting to stabilize the economy, predicting that Argentina could enter a period of growth at the end of 2024.

In 2025, América is expected to maintain a favorable stance toward President Milei’s government, marking a strategic shift in its editorial direction.

He defended the practice of people marrying after separation, and this defense coupled with his support of individual liberty was documented in a speech he gave on August 19, 1986, where he affirmed his belief in the importance of responsible liberty:[51]"We want adult liberty, responsible freedom for the Argentines, and that those who want to re-bet on love and family, instead of having the comfortable situation of separation without assuming responsibilities, to assume together with Argentine society these two issues, that we do not understand separated because in the justicialismo we learned to live them together: freedom and responsibility (...) When we speak of liberation, we are referring to the fact that as a nation and as a people each of us has to opt for more things every day, that every day he must make the renunciation that he must make to his individual freedom in order to build together collective freedom.

"In 1991, as Minister of the Interior and leader of the federal security forces, he played a key role in investigating the abduction of the businessman Mauricio Macri.

In 1995, he studied English and American domestic policy at the University of San Diego, and created a consulting firm called Integra Investments S.A., where he serves as the company's president.