He is best known for playing Ricky Verona in Crank, Miguel in Cleaner (2007), Pepe in Streets of Blood (2011), Detective Martinez in El Chicano (2018), Hector Salazar in FX's Sons of Anarchy, Caesar Martinez in AMC's The Walking Dead, Duff in Standoff, and Dave in Taken (2017).

[3] He graduated from Indiana University Bloomington in 2003 with a double major in marketing and finance from the Kelley School of Business.

[4][5] Cantillo decided to pursue an acting career in New York City after taking some drama classes at IU.

[6] After acting in Off-Broadway plays in New York, Cantillo has landed guest roles on popular television series since early 2000.

They live in Santa Clarita, a town that Cantillo described to an interviewer as “kind of reminds us of Terre Haute”, his hometown.