He was born in Vienna, son of Ferdinand Philipp Joseph, 6th Prince Lobkowicz (1724–1784) and Princess Maria Gabriella di Savoia-Carignano (1748–1828).

[1] In 1786 Emperor Joseph II made him Duke of Roudnice (Herzog von Raudnitz in German, vévoda roudnický in Czech).

[2] His paternal grandparents were Phillip Hyacinth, 4th Prince of Lobkowicz, and Countess Anna Maria von Althann.

"[4][5] He was a member of the Gesellschaft der Associierten, an important concert-sponsoring organization of his time which sponsored, among other events, the 1798 premiere of Joseph Haydn's The Creation.

[8] They had twelve children, including:[1][4] He died 1816 in Třeboň in South Bohemia, and was buried in Roudnice nad Labem.