Born at Medinaceli, Old Castile (one of the former qualifying regions into which Spain was subdivided), Gikatilla was for some time a pupil of the kabbalist Abraham Abulafia, by whom he is highly praised; his kabbalistic knowledge became so profound that he was supposed to be able to work miracles, and on this account was called "Joseph Ba'al ha-Nissim".. (the Thaumaturge or literally Master of Miracles; Zacuto, Yuḥasin, p. 224a).
Like his master, Gikatilla occupied himself with mystic combinations and transpositions of letters and numbers; indeed, Abulafia considered him as the continuator of his school (Adolf Jellinek, B.H.
In different manuscripts of the work the author's name is variously written "Gribzul," "Karnitol," and "Necatil," all corruptions of "Gikatilla."
Gikatilla was a prolific writer; he wrote his first work (Ginnat Egoz, גנת אגוז) when only twenty-six.
Isaac ben Samuel of Acre in his Me'irat 'Enayyim severely criticizes Gikatilla for too free usage of the Tetragrammaton.