Joseph Hutton DeFrees (May 13, 1812 – December 21, 1885) was an American businessman and politician who served one term as a U.S. Representative from Indiana from 1865 to 1867.

His brother, John D. Defrees, was a major figure in Indiana Republican party politics.

Born in Sparta, Tennessee, DeFrees moved to Ohio with his parents, who settled in Piqua in 1819.

He was also interested in milling, the manufacture of linseed oil, and the construction of the Goshen Hydraulic Works.

This article incorporates public domain material from the Biographical Directory of the United States Congress