The Joseph Holmes House is an historic house at 144 Coolidge Hill Street in Cambridge, Massachusetts.

It was originally located on Appian Way in Harvard Square, and was moved to its present location in 1929, at which time an ell was also added.

This house is not particularly pretentious, with a five-bay facade and center entrance, and is set sideways on its narrow lot.

[2] The house was listed on the National Register of Historic Places in 1983.

This article about a National Register of Historic Places listing in Cambridge, Massachusetts is a stub.