Joseph Spiteri (born 20 May 1959) is a Maltese prelate of the Catholic Church who works in the diplomatic service of the Holy See.

After attending local seminaries he was ordained a priest on 29 June 1984 by Archbishop Joseph Mercieca in St John's Co-Cathedral in Valletta.

[2] He joined the diplomatic service of the Holy See on 15 July 1988 and fulfilled assignments in Panama, Iraq, Mexico, Portugal, Greece and Venezuela, and then worked in the offices of the Secretariat of State in Rome.

[1] On 21 February 2009, Pope Benedict XVI appointed him Apostolic Nuncio to Sri Lanka and Titular Archbishop of Serta [it].

[1] He was consecrated by Cardinal Tarcisio Bertone, with the Maltese archbishops Paul Cremona and Joseph Mercieca as co-conservators, in St John's Co-Cathedral.