Joseph Tukalskyi-Nelyubovych, (Ukrainian: Йосип Тукальський-Нелюбович; born Nenkovychi or Mutvytsia, Brest Litovsk Voivodeship, Polish–Lithuanian Commonwealth, died 26 July 1675, Chyhyryn) was a political and religious leader of the Cossack Hetmanate and the last Metropolitan of Kyiv, Galicia and all Rus in the Ecumenical Patriarchate of Constantinople in the Eastern Orthodox Church.

He was elected and ordained to the Mstislav, Mogilev and Orsha see by his predecessor Metropolitan Dionysius Balaban[-Tukalskyi] of Kyiv, who in addition to that was a relative of Joseph Nelyubovych-Tukalsky.

The Bishop of Przemyśl, Antonii Vynnytskyi, having met with failure in the place belonging to the Polish Crown, turned to the hetman of Right-Bank Ukraine, Pavlo Teteria, for support.

Knowing what kind of power the newly elected Metropolitan Joseph Nelyubovych-Tukalskyi had over the Cossacks, he invited him together with Hegumen Hedeon Khmelnytskyi to his place.

As a result of such a rehabilitation campaign, on November 29, 1665, Metropolitan Joseph Nelyubovych-Tukalskyi and Archimandrite Hedeon Khmelnytskyi took an oath "standing on their knees and placing two fingers on the cross" and assuring everyone that they would be loyal to Poland and would not communicate with its enemies, especially rebels, insurrectionists, Muscovites, and Cossacks and will listen to Hetman Teteria, living where he tells them.

This seemingly humiliating oath of the metropolitan was later printed on January 24, 1671 in the Universal decree of the Polish king Michał Korybut Wiśniowiecki and fell into the hands of the Cossack chronicler Samiylo Velychko, who hastened to include it in his work.

Under the threat of new imprisonment, Joseph Nelyubovych-Tukalsky, with only one serviceman (cheliad) in a boat, sailed down the Dnieper straight to Cherkasy, and from there he was taken to Chyhyryn to hetman Peter Doroshenko, who received him with love, gave him a court and manor estates.

The relations between Metropolitan Joseph Nelyubovych-Tukalskyi and Hetman Pyotr Doroshenko were constantly influenced by foreign policy and Chyhyryn's attitude towards the three states that wanted to take Ukraine into their hands, under the so-called protection: the Muscovite Tsardom, the Polish-Lithuanian Commonwealth, and the Ottoman Empire.

The latter behaved very cautiously and did not dare to go to Mezhyhiria, showing the Metropolitan's letter to Voivode Peotr Sheremetiev the Great, who asked Moscow whether he should meet with Joseph Nelyubovych-Tukalskyi.

The White-stoned city (Kremlin), Innocent Giesel was ordered to meet with the metropolitan without fail in matters concerning the beginning of Moscow's conflict with Doroshenko.

Subsequently, in December 1667, Moscow, through Voivode Sheremetiev, sent the nobleman Vasiliy Dubensky and rittmaster Ivan Roslavlev to Chyhyryn, who, during a meeting with Metropolitan Joseph Nelyubovych-Tukalskyi and Archimandrite Hedeon Khmelnytskyi, persuaded him to influence the hetman to break the alliance with the Sublime Porte (busurmans).