[3] She joined The Perfect Disaster in 1988 as bass guitarist, playing on the albums Asylum Road, (1988) Up (1989) and Heaven Scent (1990) before going on to form The Breeders with Kim Deal and Tanya Donelly in 1990.

In 1989, Deal asked Wiggs to join her and Tanya Donelly (of Throwing Muses) in making The Breeders’ first album Pod.

This line-up recorded the album Last Splash in 1993, which featured the hit song "Cannonball", which opens with Wiggs' highly-recognisable bass riff.

After playing the 1994 Lollapolooza Tour, The Breeders went on indefinite hiatus following the well-publicized drug problems of guitarist Kelley Deal.

Kim Deal released a solo album, the Amps, Pacer in 1995, and she resurrected the Breeders' name in the late 1990s, but neither Wiggs nor Macpherson were members of this line-up.

[citation needed] On 21 August 2009, with one day's notice and no rehearsal, Wiggs played three shows with The Breeders after then-bassist Mando Lopez had to fly home because his girlfriend had gone into labor.

In 1995, Wiggs recorded and co-produced the album Klassics with a K for the Kostars, featuring Luscious Jackson's Jill Cunniff and Vivian Trimble, and toured with them playing drums.

[6] In 1997, Wiggs started a writing and recording collaboration with Luscious Jackson keyboardist Vivian Trimble under the name Dusty Trails.

In addition, they collaborated with internationally acclaimed New York-based Brazilian choreographers chameckilerner, writing and recording full-length scores for Poor Reality, 2001, and Exit 2007.

During a relationship with drummer Kate Schellenbach, the two were featured in an article in The Advocate, a national LGBT magazine published in the United States.