Iosefa-Scott represented Waikato in the National Provincial Championship and played 41 games for them overall between 2016 and 2020.
[1] He made his debut for the Highlanders during the 2019 Super Rugby season and earned a second and last appearance the following year.
[1][2] In the summer of 2021 it was announced that Iosefa-Scott had signed for Exeter Chiefs and he made his debut at the start of the 2021–2022 season in a league fixture against Northampton Saints.
[1][3] In March 2023 he was a second-half substitute as Exeter defeated London Irish after extra time in the final of the Premiership Rugby Cup.
[4] The following month saw him score a try in the semi-final of the European Rugby Champions Cup as Exeter were eliminated by holders La Rochelle.