[4] On 21 September 2021, he made his professional debut when he was named in the starting line up for Manchester City's EFL Cup tie against Wycombe Wanderers.

[6] On 10 January 2023, Wilson-Esbrand joined EFL Championship club Coventry City on a loan for the remainder of the 2022–23 season.

[11] On 22 January 2025, Wilson-Esbrand was loaned out to EFL Championship club Stoke City until the end of the 2024–25 season.

[12][13] On the same day, he made his debut for the club in a 3–1 away defeat against Portsmouth, providing the assist to Ben Wilmot for Stoke's only goal of the game.

[16] On 19 November 2023, Wilson-Esbrand made his England U21 debut as a substitute in the 3–0 2025 UEFA European Under-21 Championship qualification victory away to Serbia.