Jothimani was born on 9 August 1975 at Periya Thirumangalam, Aravakurichi, Karur District to Sennimalai and Muthulakshmi.

With the support of her mother Muthulakshmi, she completed her Graduation at Sri G.V.G Visalakshi College for Women, Udumalaipet.

[4] Jothimani then unsuccessfully contested the 2011 Tamil Nadu Legislative Assembly election after securing the Indian National Congress' candidature from Karur constituency.

Her Facebook and Twitter account with the hashtag, 'Aravakurichi 2016,' are replete with postings and pictures of her interaction with voters of the constituency.

When Aravakurichi did not figure on the Congress list, Jothimani unleashed a volley of strong criticisms and even threatened to contest as an independent candidate.

In what was seen as a major upset by many media outlets and political analyst, Jothimani went on to defeat veteran All India Anna Dravida Munnetra Kazhagam leader, M. Thambidurai who had previously served as Deputy Speaker of the Lok Sabha Speaker and in the Union Cabinet.