The journal publishes reports of empirical studies, critical reviews of the literature, contributions related to theory, open peer commentary articles, and editorials on what are deemed to be significant issues.

[1] The articles were mostly critical of the PACE trial, and the journal concluded that "the results are, at best, unreliable, and at worst manipulated to produce a positive-looking outcome".

However, three editorial board members of the journal, all of whom were alleged to have conflicts of interest, resigned in protest, claiming that the articles were biased and one-sided.

In response, an associate editor of the journal, James C. Coyne, attacked the three resigning board members, calling one a "disgusting old fart neoliberal hypocrite", and telling another to "f*** off...you ol' sleazebag".

"[5] In 2019, the journal published a review article by Anthony J. Pelosi that delivered a significant criticism of the work of the late Hans Jürgen Eysenck, referring to it as "one of the worst scientific scandals of all time" and calling for a "long-overdue formal investigation.