The journal covers any Africa-related topic: political, social, economic, environmental and historical.

[2] The journal's initial scope was defined as covering "many subjects in Africa, such as Racial Characteristics, Labour, Disease, Currency, Banking, Education and so on", to which was later added, "Political and Industrial Conditions".

[2] Popular topics for early papers were ethnography and African languages, which between them made up around 60% of the content during its first ten years.

[2] Past editors include Alice Werner, Henry Swanzy (1944), Alan Gray (1954–1966), Tom Soper (1966), Alison Smith, Richard Rathbone (1969), Michael Twaddle, Anthony Atmore, Richard Hodder-Williams, Peter Woodward, David Killingray, Stephen Ellis, Tim Kelsall, Sara Dorman, Nic Cheeseman, Rita Abrahamsen, Lindsay Whitfield, Carl Death and Peace Medie (2017), the first editor to be an academic from Africa.

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