[2][3][4][5] Eyisi is a native of Eziora Village of Adazi-Ani in Anaocha Local Government Area of Anambra State, located in the southeastern region of Nigeria.
[6][7][8] Her only daughter (Joy Eyisi, Jnr, the author of Willy-Nilly, a novel that is classified as Nigerian children's literature of the 21st century) is a first-class degree graduate in English from Covenant University, Ota, Ogun State, Nigeria.
In the same year, with a better Common Entrance Examination result, she was admitted to Girls’ High School, Agulu, which was then under the leadership of Rev (Sr) Miriam Theresa Ozomma.
She went for further studies at the University of Nigeria, (UNN), Nsukka, Enugu, graduating with a bachelor's degree (Second-Class Upper Division) in Education and English.
After her national service in 1994, she was admitted for a master's degree programme in Education Administration and School Supervision, Nnamdi Azikiwe University, from where she graduated as the overall best student amidst a nation-wide ASUU strike of 1995.
Eyisi's influence brought about the construction of the Department of English Language and Literature (situated close to Nnamdi Azikiwe University's Faculty of Law) by a Nigerian transporter, Chief Godwin Ubaka Okeke (MON).
[12] As a scholar, Eyisi is known to have authored, co-authored, and edited several academic articles, journals, textbooks, motivational booklets, and conference presentations that are widely cited.
[19] In ‘’The Role of Women in Empowering Change’’, which she delivered in a workshop, Eyisi avers that childbearing should not be an excuse for furthering education, advocating that: “A girl child should be given the opportunity to be educated, she should go to school, she should acquire education.”[20] As part of her contributions to education and the society generally, Eyisi, in 2004, received Silver Jubilee Merit Award from Bishop Crowther Seminary, Awka; 2005 Adadiebube: Recognition and Merit Award from St. Jude’s Anglican Church Adazi-ani Women's General Meeting (Home and Abroad); Great Woman of Honour Recognition and Merit Award from BBC Club, UNIZIK, Awka (2005); a Menu of Integrity, Merit and Certificate from Rotary International, Rotary Club of Awka, District 9140 (2006); Doyenne of Excellence, Distinguished Scholarship Award, from English Language Teachers Association of Nigeria (2007).