Wong is an accomplished cellist – in 1984 she was a finalist in the Seventeen Magazine & General Motors National Concerto Competition, and during her undergraduate and graduate career was a member of the MIT Chamber Music Society.

[1] Wong was appointed a National Institutes of Health postdoctoral fellow at University of California, Santa Barbara working under Jacob N. Israelachvili.

Her doctoral research investigated electrically conducting polymers, identifying that they can be used as a culture substrate to modulate the shape and growth of mammalian cells.

[3] She also developed polymer cushioned bilayers as model cell membrane systems and characterized their biophysical properties using the surface forces apparatus and neutron reflectometry.

[28] Using tools developed to describe the silk's structure and drawing on her musical training, Wong enlisted composer John MacDonald (Tufts University), who translated the structure of different silk protein fragment sequences into a series of musical compositions for flute.

[29] Wong's most recent work has been developing targeted ultrasound[30][31][32] and magnetic resonance (MR)[33][34] contrast agents for the early detection of disease.

[35][36][37] She is currently conducting pre-clinical studies of targeted ultrasound contrast agents in collaboration with Nanovalent Pharmaceuticals[38] to detect and treat surgical adhesions.

In 2018 she was elected to the Council of the Tissue Engineering Regenerative Medicine International Society (TERMIS) - North America.