He was an advocate for the reform of the Constitution of Argentina in 1860, chief of staff of the Argentine Army during the Paraguayan War as well as a personal friend of Bartolomé Mitre.

He was appointed Chief of Staff of the Argentine Army campaigning in Paraguay, which was why he resigned from his post as minister and then participated in the Battle of Tuyú Cué.

Some years later, he was the head of the national forces in Corrientes, where he fought General Nicanor Cáceres, who was trying to defend the constitutional governor from a revolution supported by President Mitre.

[3] He remained in the Corrientes Province, as chief of the army reserve in campaign, until the outbreak of the Jordanist Rebellion, directing one of the main columns in the war against him.

He controlled part of the north of the Entre Ríos Province until the Battle of Don Cristóbal where he was defeated by López Jordán, although the latter had to withdraw at the end of the day due to the approach of more government forces.