In 1907, he enrolled in a medical school in Puebla, where he started political and military opposition against the dictator Porfirio Díaz.

[6] When Huerta was defeated in August 1914, Andreu Almazán and several other generals associated with Orozco, and known as "Colorados," because of their red flag, moved south and joined forces with Zapata.

[8] The glory was short-lived, however, because the following month, General Alvaro Obregon's Constitutionalist Army forced Almazán and the Colorados out of Puebla.

[10] Throughout 1915, 1916, and 1917, Andreu Almazán operated in the area of Guerrero, Puebla and Oaxaca, primarily as an independent rebel force, yet putting out public pronouncements that he supported either Zapata or Díaz.

[12] With the Agua Prieta revolt of 1920, Andreu Almazán supported the rebel forces that removed Carranza and established Obregón as President.

In the 1920s, he became the director and main stockholder of a roadbuilding firm and began investing his profits in industrial and real estate holdings in Monterrey, Mexico City, and Acapulco.

He was loyal to President Plutarco Calles, and as Communications Minister in Ortiz Rubio's cabinet in the early 1930s, he enlarged his already-considerable fortune by granting government concessions, such as the Pan American Highway construction job from Laredo to Mexico City to his own company.

[citation needed] Alleging fraud, Andreu Almazán traveled to Cuba and later to the United States to meet with officials of the administration of President Franklin Roosevelt and to probe his position in the face of an eventual Almazanist revolution.

Although the US government did not look favourably on Cárdenas's radical socialist positions, it was annoyed by Andreu Almazán's alleged friendship with the retired anti-Semitic and openly-fascist US General, George Van Horn Moseley.