Arvizu first appeared with Pierson's opera company while performing on stage with the noted soprano Ángeles Ottein and Consuelo Escobar.

He visited New York City during this time and continued to augment his operatic repertoire to include the Argentine tango and the works of María Grever and Alfonso Esparza Oteo.

By 1927, Arvizu returned to Mexico and appeared in another operatic production at the Teatro Esperanza Iris of Giacomo Meyerbeer's work Dinorah.

[4] While Arvizu's natural vocal qualities and the power of his operatic voice attracted the attention of the public, he faced financial obstacles in his professional endeavors at this time.

The composer Jorge del Moral entrusted his composition Por Unos Ojos to Arvizu, whose vocal versatility and musical qualities earned him the nickname "The Tenor With the Silken Voice".

[12] Years later in 1942 he premiered with the Cadena de Las Amėricas of the Columbia Broadcasting System (CBS) and Voice of America on the Viva América show in New York, in collaboration with the orchestra conductor Alfredo Antonini, the Puerto Rican vocalist Elsa Miranda, the Argentine composer Terig Tucci, the Mexican American vocalist Eva Garza and the concert accordionist John Serry Sr.[13][14][15][16][17][18] In 1941 he also collaborated with the Andre Kostelanetz Orchestra in live performance on the radio for WABC in New York City.

[29] Along with other leading vocalists of the time such as Pedro Vargas and Alfonso Ortiz Tirado, Arvizu helped to popularize several of Lara's greatest compositions.

[30][31] They included such works as: Aventura, Concha Nacar, Cuando Vuelvas, Enamorada, Granada, Santa and Tus Pupilas.

After a long tour in his native town of Queretáro, Mexico in 1967, he embarked upon a period of rest since his life had been characterized by continuous movement.

He often premiered compositions by several prominent Latin composers including: Mario Clavell from Argentina, Rafael Hernández Marín from Puerto Rico, Donato Roman Heitman from Chile, Enrique Fábrega from Panama, Carlos Vieco, Augusto Duque from Colombia, and Agustín Lara, Gonzalo Curiel and Gabriel Ruiz Galindo from Mexico.

His recordings with Margarita Cueto include several famous songs such as: Taboga, Más Vale Tarde Que Nunca, Bajo el Palmar, Deseparacíon, among many others.

Among some of the most popular titles are his interpretations of: Arrepentimiento Cada Vez Que Me Recuerdes, Corrientes y Esmeralda, Qué Fácil Es Decir, La Cumparsita, Lágrimas de Sangre, Madreselva Caminito, Mi Buenos Aires Querido, Mi Único Amor, Nido Gaucho, No Cantes Ese Tango, Nuestra Casita, Pecado, Plegaria, Prohibido, Salud Dinero y Amor, Señior Juez, Si Dejaras de Quererme, Sinceramente, Tengo Mil Novias, Verdemar, Una Cación.

The song tells the tale of a boy who was selling colored strips of paper and subsequently suffers a fatal accident caused by a vehicle which is driven by a pierrot at a carnival.

In Cuba, Arvizu starred in the most important film of his career Ahora Seremos Felices with the charismatic Puerto Rican artist Mapy Cortés.

Arvizu sang several boleros by the composer Rafael Hernández including: Quiero Decirte, Las Palomitas, Purísima and Ahora Seremos Felices.

[50][51][52][53] During the course of his long career recording music for the Victor label, Arvizu's performances were reviewed by critics in such leading magazines as The Billboard.