Born in 1978 in the ESMA clandestine detention center, Cabandié is the son of two "desaparecidos", alleged political dissidents of the military dictatorship that ruled Argentina from 1976 to 1983.

[5] Cabandié's doubts on his identity led him to press his parents on the subject, and eventually, in 2003, Parrone de Falco admitted the truth to him.

[2] Luis Antonio Falco was sentenced to 18 years in prison by a Buenos Aires tribunal in 2011 for the crimes of appropriation of minors and suppression of identity.

[8] From then on, he began to be more and more involved in politics and eventually became one of the co-founders of La Cámpora, the main youth wing of the Front for Victory (FPV) and the Kirchnerist movement, alongside Máximo Kirchner, Eduardo de Pedro, and Mariano Recalde, and others.

[10][11] Ahead of the 2007 elections in Buenos Aires, Cabandié ran in the Front for Victory list to the City Legislature as the fourth candidate.

Although the FPV only received enough votes to win three seats in the Legislature, one of the elected candidates, Ginés González García, took up the position of Argentine ambassador to Chile and so Cabandié was sworn in in his stead.

As minister, Cabandié overturned a decree signed by former president Macri that loosened restrictions on the import of plastic waste.