[2] She was a Special Intern at the Library of Congress after serving as a cataloguer in 1964–65 at the Johns Hopkins University Bologna Center in Italy.
At the Library of Congress, she was a cataloguer in the Prints & Photographs Division until 1967, when she served as the Fine Arts Librarian at the University of Pennsylvania from 1967 to 1969.
She went on to UCSD from 1969 to 1971 as art, literature and language bibliographer and to the Brand Library in Glendale, CA as Director from 1971 to 1973.
From 1974 to 1976, she worked for the Smithsonian Institution as Archivist and Editorial Assistant for the Bicentennial Bibliography of American Arts.
[5] In 2000, Hoffberg and Béatrice Coron founded the International Edible Book Festival.