[3] It is found in the Pacific Ocean, including off the coasts of New Zealand[4] as well as in the Yellow Sea and surrounding Chinese shores.

[5][6] Individuals of A. fangsiao that share genetic similarities by region are distributed throughout the Yellow Sea by size.

[9] This species occurs in the Philippine Sea, the northwest Pacific and off the coast of Japan (Osaka Bay).

[5] The embryos that grew at 27 °C (81 °F) were not able to hatch due to accelerated growth which caused eggs to be more swollen than eggs developing at lower temperatures; this accelerated growth caused the chorion to break and the embryo to hatch prematurely.

It is known that is that these parasites belong to the genus Aggregata and are responsible for the infections that have led to the death of many A. fangsiao in a culture facility in China.

[11] Evidence of the parasite's infection on the A. fangsiao specimens include numerous white cysts scattered throughout the body of each octopus.

[11] These data showed that the death rate of females was higher than males during their breeding season.

[7] In Korea, Amphioctopus fangsiao is called jukkumi (주꾸미) or jjukkumi (쭈꾸미) and is often stir-fried in spicy gochujang-based sauce.