Lord Oxford's two older sisters both predeceased him; the younger of these was Lady Perdita Rose Mary Asquith, later Lady Hylton (1910–1996),[1] who was married to William Jolliffe, 4th Baron Hylton and became the grandmother of the actress Anna Chancellor.

In 1936, he attended the opening of the new building of Campion Hall, a Catholic institution within the University, with the Duke of Alba, Spanish ambassador to London, and Alban Goodier S.J., the former Archbishop of Bombay.

[2] In 1940, Asquith was commissioned in the Royal Engineers and served with 3 Field Squadron in Egypt.

Oxford was the Governor and Commander-in-Chief of the Seychelles from 1962 to 1967, and the Commissioner of the British Indian Ocean Territory from 1965 to 1967.

Lord and Lady Oxford had five children: three daughters (the second of which is married to a diplomat)[citation needed] and two sons, both diplomats: Lord Oxford inherited the estate of Mells Manor from his mother Katharine Asquith, the younger daughter of Frances Jane (née Graham) and Sir John Francis Fortescue Horner.