Created by J. J. Abrams and Damon Lindelof, the character was introduced in the third season as a member of the hostile group referred to as "the Others" by the crash survivors of Oceanic Flight 815.

Flashbacks reveal Juliet's past as a research specialist recruited to solve the Island's fertility problem where pregnant women die after conception.

Juliet initially grows close to the castaways' leader, Jack Shephard, but ultimately falls in love and forms a relationship with James "Sawyer" Ford, with whom she moves on to the afterlife in the series finale.

As a child, Juliet Carlson is devastated to learn her parents (Michael Trisler and Amy Stewart) are getting a divorce; her mother explains that although they love each other, they are not meant to be together.

Richard and Ethan Rom (William Mapother) show up at the morgue to offer Juliet another chance to accept the job to which she agrees, believing it would only last six months somewhere "not quite in Portland.

[4] In September 2001, after the six months on the Island that she agreed to passes, Juliet tells Ben the fertility problem causing pregnant women to die occurs during conception.

At the Flame station, Mikhail Bakunin (Andrew Divoff) shows Juliet live footage of a cancer-free Rachel with her two-year-old son, Julian, presumably named after her.

[4] After they abduct Walt Lloyd (Malcolm David Kelley) and keep him in "Room 23", Juliet supervises him and realizes he is "dangerous", noting the pile of dead birds outside his cell.

[13] Jack agrees to do the surgery but ends up slitting Ben's kidney sac to blackmail the Others into letting James "Sawyer" Ford (Josh Holloway) and Kate Austen (Evangeline Lilly) go.

Ben wakes up during the surgery and concedes to Jack's demands, privately asking Juliet to help Sawyer and Kate escape in exchange for her freedom and finally letting her off the Island.

[16] Prevented from leaving the Island once more, Juliet is asked by Ben to infiltrate the survivors' camp, gain their trust and mark the tents of their pregnant women so the Others can kidnap them.

The Others activate an implant they previously placed in Claire Littleton (Emilie de Ravin), allowing Juliet to help her by offering a prepared solution, thereby gaining the survivors' trust and respect.

[18] Upon learning that Sun-Hwa Kwon (Yunjin Kim) is pregnant, she takes her to the Staff station to perform an ultrasound; Juliet confirms that Sun conceived on the Island, giving the latter two months left to live until her second trimester.

[24] When Karl Martin (Blake Bashoff) warns of the Others' early arrival at the behest of Alex Rousseau (Tania Raymonde), the survivors move up their schedule and divide into three groups: Sayid, Jin-Soo Kwon (Daniel Dae Kim) and Bernard Nadler (Sam Anderson) remain at the beach camp to spring the trap; Charlie Pace (Dominic Monaghan) and Desmond Hume (Henry Ian Cusick) follow Juliet's instructions to breach the Looking Glass station and disable its signal jammer; and Jack and Juliet lead the rest of the group to the Island's radio tower in hopes of using Naomi's satellite phone to call for rescue.

[25][26] Juliet and the survivors on the beach reunite with Desmond who reveals that before Charlie died, he warned that Naomi and her crew on the Kahana freighter are not on the Island to rescue the castaways.

All of the survivors rendezvous in the jungle and fracture into two groups: Jack's camp heads back to the beach to negotiate rescue with the freighter; while Locke, believing that those arriving on the Island intend to do them harm, leads his faction to the Others' former Barracks.

[27] She and Sayid express their distrust of the newcomers and track Jack down in the jungle, where he and Kate are being held at gunpoint by two of the Kahana's science team, Daniel Faraday (Jeremy Davies) and Miles Straume (Ken Leung).

Juliet is confronted by Harper — her former therapist — on the behalf of Ben, who warns that Daniel and Charlotte intend to release a chemical gas at the Tempest station that will kill everyone on the Island.

[32] When the corpse of freighter doctor Ray (Marc Vann) washes ashore, Juliet and Jack interrogate Daniel who reveals they never intended to rescue anyone on the Island.

Sayid returns in the Zodiac raft to start ferrying people at the beach camp to the Kahana, revealing that Charles Widmore's (Alan Dale) mercenaries, led by Martin Keamy (Kevin Durand) on the chopper, intend to kill the survivors; Juliet insists that Sun boards the raft first since she is pregnant and tells Daniel she will not leave the Island until everyone is safe aboard the freighter.

Remaining on the Island well beyond her initial two-week promise, Juliet works as an auto mechanic while Sawyer serves as head of security under the name "Jim LaFleur"; the pair are in a relationship and share a house at the Barracks.

Agreeing "it's wrong to let a child die" even if he will grow up to cause them harm, Juliet and Sawyer take Ben to the Others, who are able to save his life at the cost of his innocence.

[48][49] When they are interrogated by Radzinsky and Dr. Pierre Chang (François Chau), Sawyer agrees to reveal Jack's location if he and Juliet are allowed off the Island on the Dharma submarine.

In the "flash sideways timeline", Dr. Juliet Carlson works as a maternity doctor at St. Sebastian Hospital in Los Angeles, California, alongside Jack, who is her ex-husband.

They realize the "flash sideways" is, in fact, a purgatory the survivors on the Island created so they could find each other after death and move on together; physical contact with one's "constant" (the person one loved the most) would "awaken" them and cause them to "remember".

As Christian Shephard (John Terry) opens the church doors, a glowing white light flows in and Juliet and Sawyer move on to the afterlife together as soulmates.

[58] Her character, Dr. Juliet Burke, was conceived by the writers as the bridge between the Others and the survivors as well as the next possible love interest for Jack, though her arc was further developed and expanded upon as the story progressed.

"[74] The display of the character's "more human side" through flashbacks in "Not in Portland" was lauded by IGN's Chris Carabott, who deemed the episode worthy of getting viewers "back on the Lost hype train.

"[72] BuddyTV Senior Writer Jon Lachonis also complimented Mitchell's "sensitive, enigmatic portrayal" of Juliet in "One of Us", which he called "the most perfect episode of Lost ever produced, bar none.

[78] Mitchell submitted her performance in the episode "One of Us" for consideration on her behalf in the category of "Outstanding Supporting Actress in a Drama Series" at the 2007 Emmy Awards,[79] but was not nominated.