Juliet Ann Hopkins (née Opie; May 7, 1818 – March 9, 1890) was an American nurse and philanthropist, who set up three hospitals in Alabama in the 1860s.

During the Civil War, the couple sold most of their real estate holdings and donated the money to the cause of the Confederate States of America.

When she died, she was interred with a full military burial at Arlington National Cemetery, with the Alabama congressional delegation serving as her pallbearers.

Juliet Ann Opie was born in 1818 on her parents' Jefferson County, Virginia plantation "Woodburn", which employed slave labor.

Operating out of a supply depot in Richmond, she converted three tobacco factories into hospitals during the four-month period of December 1861 through April 1862.

The three facilities served an aggregate case load exceeding 500 patients and were daily overseen by on-site visits from Juliet.

[8] Wilson's Raid throughout Alabama sites in March and April 1865[9] forced the Hopkinses to flee the state and take refuge in Newman, Georgia.

[10] Juliet relocated to New York to live on property that had not been sold for the war effort, her remaining years spent in poverty.