Caring for her terminally ill husband writer Jonas Biliūnas, she lived and worked in Zakopane.
During World War II, she helped hide five Jews for which she was awarded the Life Saving Cross [lt] in 2002.
There she helped store and distribute social democratic publications and joined a circle of Lithuanian intellectuals, including Povilas Višinskis and Liudas Vaineikis.
At the same time, as an extramural student, she finished four classes at the newly established Šiauliai Girls' Gymnasium.
She then further completed two-month dental courses in Vilnius and opened a private practice in Panevėžys in spring 1902.
For some time, she worked as a dentist for the Lithuanian Society for the Relief of War Sufferers and had a private practice in Voronezh.
[2] In 1918, Biliūnienė returned to Vilnius and joined the hospital of the Lithuanian Sanitary Aid Society which was chaired by her brother-in-law Danielius Alseika.
[5] Biliūnienė lived with her sister Veronika Alseikienė and their daughters Meilė Lukšienė and Marija Gimbutas had a formative influence on each other.
[6] In the Lithuanian SSR, she could no longer have a private practice but continued to see patients (family and friends) until the age of 92.
She maintained contacts with remaining members of Lithuanian intelligentsia – families of sculptor Petras Rimša, painter Antanas Žmuidzinavičius, naturalist Tadas Ivanauskas, writer Sofija Kymantaitė-Čiurlionienė.