He played briefly for the American National Basketball Association's San Antonio Spurs during the 1994–95 NBA season.

[1] Born in Nkwere, Nigeria, Nwosu attended Liberty University in Lynchburg, Virginia.

Nwosu led the Red Bull Thunder to the PBA Commissioner's Cup title in 2002.

In 2005, he started with Asesoft Ploiesti in Romania (averaging 12.8 points and 9.8 rebounds in FIBA Europe Cup), before signing with Syrian club Al Jalaa Aleppo in February 2006.

But due to bad medication bought at a market in Lagos, he was suspended for doping and could not finish the tournament.