[1] The by-elections were held on these seats: PP-7 (Rawalpindi-II), PP-83 (Khushab-II), PP-90 (Bhakkar-II), PP-97 (Faisalabad-I), PP-125 (Jhang-II), PP-127 (Jhang-IV), PP-140 (Sheikhupura-VI), PP-158 (Lahore-XV), PP-167 (Lahore-XXIV), PP-168 (Lahore-XXV), PP-170 (Lahore-XXVII), PP-202 (Sahiwal-VII), PP-217 (Multan-VII), PP-224 (Lodhran-I), PP-228 (Lodhran-V), PP-237 (Bahawalnagar-I), PP-272 (Muzaffargarh-V), PP-273 (Muzaffargarh-VI), PP-282 (Layyah-III) and PP-288 (Dera Ghazi Khan-IV).

The by-elections were triggered after these 20 PTI MPAs voted in favor of the opposition candidate belonging to the PML(N), Hamza Shahbaz, to become the Chief Minister of Punjab, which, according to the Supreme Court and the Election Commission of Pakistan, violated Article 63-A of the Constitution of Pakistan which concerns party defections.

During a political crisis in Pakistan after the successful no-confidence motion against Prime Minister Imran Khan, another motion of no confidence was filed against Chief Minister Usman Buzdar, as well as against Chaudhry Pervaiz Elahi and Dost Muhammad Mazari, the Speaker and Deputy Speaker of the Provincial Assembly, respectively.

Buzdar resigned before a vote on the motion of no confidence could be held and as a consequence, an election for a new Chief Minister was scheduled on 16 April between PML(N)'s Hamza Shahbaz, the joint candidate of the Pakistan Democratic Movement, and PML(Q)'s Chaudhry Pervaiz Elahi, the joint candidate of his party and PTI.

On the day of the election, 25 PTI MPAs crossed the floor to support Shahbaz, violating party policy.

[3] The Deputy Speaker then presided over the Assembly session in the visitors gallery and declared Shahbaz the winner by securing 197 votes.

% Detailed results of each constituency are as follows: In the aftermath of the by-election, it was claimed that PTI MPA from PP-257 (Rahim Yar Khan-II), Chaudhry Masood Ahmad had become a turncoat after his loyalty was allegedly bought, whereafter he soon fled to Turkey.

[14] Allegations of rigging were also put forward by PTI in the PP-7 (Rawalpindi-II) constituency, where the PML(N) candidate emerged as the victor with a margin of 49 votes.

[16] 2 PML(N) MPAs, Faisal Niazi from PP-209 (Khanewal-VII) and Jaleel Ahmed Sharaqpuri from PP-139 (Sheikhupura-V), also resigned from their seats before the election for Chief Minister.

[19] Controversially, the votes of ten PML(Q) MPAs were rejected by Deputy Speaker Dost Muhammad Mazari, citing an interpretation of Article 63A of the Constitution and a letter from the leader Shujaat Hussain stating he had "issued directions to all my provincial members to cast their votes in favour of Muhammad Hamza Shahbaz Sharif".