She attended Talent Unlimited High School and after graduation worked for a brief period in investment banking before interning at MCA Records where she began styling new artists.

[6] She attended Talent Unlimited High School at the Julia Richman Education Complex where she began designing costumes for theater productions.

[7][5] After graduation, she went to work as an office administrator at S. G. Warburg & Co. for two years before securing an internship at MCA Records where she began styling artists for the label.

[5] She describes being initially inspired by "Japanese animation and old movies"[2] and as of 2021 has designed for over 200 music videos,[8][9] most notably creating Missy Elliott's patent leather blow-up bodysuit in "The Rain (Supa Dupa Fly)"; Sean "Diddy" Combs' suit in "Mo Money Mo Problems" and Busta Rhymes' kaftan in "Put Your Hands Where My Eyes Could See".

[12][8] Ambrose was the costume designer for the 1998 film Belly, directed by Hype Williams, with whom she frequently collaborated,[8][7] and a stylist for The X-Factor in 2011.