When she was a teenager, MacCloy impersonated Broadway star Harry Richman,[2] singing in George White's Scandals (1928).

Subsequently, MacCloy appeared in a variety of shorts and some features with stars such as Jack Oakie, Frances Dee and ZaSu Pitts.

MacCloy is probably best remembered today for her last major film role as Lulubelle, the saloon girl in Go West (1940), starring the Marx Brothers.

MacCloy subsequently sang with dance orchestras, including Johnny Hamp, Henry King, Jimmie Grier and Ben Pollack.

In San Francisco she was featured with the Williams-Walsh Orchestra (Griff Williams and Jimmy Walsh) at the Hotel Mark Hopkins.