His longest spell was at Bristol Rovers (2003–2006), where he made 140 appearances and scored over 40 goals before moving to Nottingham Forest.

His three goals in the final stages of the 2008 Africa Cup of Nations helped Ghana to a third-place finish, adding to the three club honours he earned during his career.

[4] In 2000, Agogo left Sheffield Wednesday and moved to the United States to play for the Chicago Fire of Major League Soccer.

After playing just one match in Chicago, he was traded to the Colorado Rapids to replace the departed attacker Wolde Harris who had just joined New England Revolution.

He played for the Earthquakes for the rest of the 2001 season, culminating with their MLS Championship victory, but was waived early in the 2002 pre-season, and replaced on the San Jose roster by Devin Barclay.

[10] In the summer of 2003, Agogo joined Third Division side Bristol Rovers for £110,000 with Giuliano Grazioli going to Barnet in the opposite direction.

However, Agogo scored only three goals after his return from the 2008 Africa Cup of Nations, one of which was against Leyton Orient at Brisbane Road.

He finished as Forest's top-scorer that season with thirteen goals, helping the club gain automatic promotion to the Championship.

He played in the first game of the cup against Guinea, hitting the post with a header in the 20th minute and helping Ghana to a 2–1 victory.

He subsequently returned to Ghana for three years, attending St. Augustine's College, an all-boys Catholic boarding secondary school in Cape Coast.

[36][38][10] On 20 September 2019, Agogo's remains were cremated in London after a private funeral ceremony at St Mark's Church.

On 26 August 2019, four days after his death, Nottingham Forest fans paid tribute to the striker in the 23rd minute of their match against Derby County in the Carabao Cup.

[41][42][43] Bristol Rovers players wore number 9 shirts adorned with Agogo's name during their warm-up before their match against Oxford United on 24 August 2019.

Prior to kick-off, both sets of players stood around the centre circle and applauded for a minute while the message "RIP Junior Agogo" was displayed on the scoreboard.